Description
Alluzience 125 Speywood units: Ready-to-Use Botulinum Toxin Solution
What is Alluzience?
Alluzience 125 Speywood units is the first ready-to-use liquid formulation of botulinum toxin type A (BoNT-A) approved for aesthetic use. Unlike traditional botulinum toxin products that come in powder form requiring reconstitution, Alluzience comes in a pre-diluted, ready-to-use solution. This liquid formulation eliminates the need for reconstitution before injection, potentially improving consistency in preparation and administration.
Developed by Galderma, Alluzience is specifically indicated for the temporary improvement in the appearance of moderate to severe glabellar lines (vertical frown lines between the eyebrows) seen at maximum frown in adult patients under 65 years of age.
What is Alluzience 125 Speywood Units?
Alluzience 125 Speywood units contains botulinum toxin type A (BoNT-A) measured in Speywood units. Each vial of Alluzience contains 125 Speywood units of botulinum toxin type A in a 0.625 ml solution.
It’s important to note that Speywood units are specific to Alluzience and Dysport (another Galderma product) and are not interchangeable with other botulinum toxin products that use different units of measurement. The potency of Speywood units differs from that of Botox® units (Allergan) or Xeomin® units (Merz).
Alluzience 2×125 Units Twin Pack
The Alluzience 2×125 Units Twin Pack contains two vials of the product, each containing 125 Speywood units of botulinum toxin type A. This packaging option provides practitioners with more product for treating multiple patients or for patients requiring treatment in multiple areas. The twin pack can be more economical for clinics with high patient volume.
Alluzience 125 Speywood units Dosage
The recommended dosage of Alluzience depends on the treatment area and the individual patient’s needs. For glabellar lines (frown lines between the eyebrows), the standard recommended total dose is 50 Speywood units, divided into 5 injection points.
Typically, the dosage is distributed as follows:
- 10 Speywood units in each of two injection points in the corrugator muscles
- 10 Speywood units in each of two injection points in the procerus muscle
- 10 Speywood units in one injection point in the orbicularis oculi muscle
For optimal results, the treatment should be repeated every 3-4 months, or as determined by your healthcare provider based on individual response to treatment.
Alluzience 125 Speywood units Dosage Before and After
Before Treatment: Prior to administering Alluzience, practitioners should:
- Assess the patient’s facial anatomy and muscle activity
- Discuss the patient’s aesthetic goals
- Review medical history for contraindications
- Determine the appropriate dosage based on muscle mass and strength
After Treatment:
- Results typically begin to appear within 2-3 days after injection
- Maximum effect is usually observed within 7-14 days
- The aesthetic improvement generally lasts 3-4 months before gradually diminishing
- Patients should follow post-treatment instructions, including avoiding:
- Touching or massaging the treated area for 24 hours
- Strenuous exercise for 24 hours
- Lying down for 4 hours after treatment
Visible improvements after Alluzience treatment include:
- Reduction in the appearance of frown lines
- Smoother forehead appearance
- More relaxed and refreshed facial expression
- Natural-looking results when properly dosed
Botox Alluzience: Understanding the Differences
While both Botox and Alluzience contain botulinum toxin type A, there are several key differences between these products:
Feature | Alluzience | Botox |
---|---|---|
Formulation | Liquid, ready-to-use | Powder, requires reconstitution |
Unit measurement | Speywood units | Allergan units |
Onset of action | Potentially faster (2-3 days) | Typically 3-5 days |
Diffusion | May have greater diffusion | More localized |
Approved indications | Glabellar lines (in Europe) | Multiple cosmetic and medical indications |
Preparation time | None required | Requires mixing with saline |
It’s crucial to understand that the units between these products are not equivalent or interchangeable. One Allergan unit (Botox) is not equal to one Speywood unit (Alluzience).
Alluzience Botox Price
The cost of Alluzience treatments varies widely depending on geographic location, clinic reputation, practitioner expertise, and the treatment area. As a general guideline:
- Single area treatment (e.g., glabellar lines): $250-$400
- Multiple area treatments: $500-$800+
- Alluzience 2×125 Units Twin Pack (for practitioners): $400-$600
Many practitioners price their treatments based on units used rather than by area, with Alluzience typically costing $10-$15 per Speywood unit.
Compared to traditional Botox treatments, Alluzience may be:
- Similarly priced in some markets
- Slightly higher priced in others due to its ready-to-use convenience
- More cost-effective for practitioners due to reduced preparation time and waste
Always consult with qualified practitioners for accurate pricing in your specific location.
Alluzience 125 Speywood units Approval Status
Alluzience 125 Speywood units received CE mark approval in Europe in 2020, making it the first ready-to-use liquid neuromodulator available for aesthetic use in the European market. It is approved for the temporary improvement in the appearance of moderate to severe glabellar lines in adult patients under 65 years of age.
The approval was based on clinical studies demonstrating its safety and efficacy profile. Key milestones in Alluzience’s approval journey include:
- European approval: 2020 (CE mark)
- UK availability: 2021
- Other European countries: Gradual rollout since 2021
As of 2023, Alluzience is not yet FDA-approved in the United States, though Galderma continues to work toward expanding its global availability.
Alluzience 125 Speywood units vs Dysport: Key Comparisons
Both Alluzience and Dysport are manufactured by Galderma and contain the same active ingredient (botulinum toxin type A) measured in Speywood units, but they differ in several important ways:
Formulation
- Alluzience: Ready-to-use liquid solution
- Dysport: Powder requiring reconstitution with saline
Concentration
- Alluzience: 200 Speywood units per ml
- Dysport: Variable, depending on reconstitution ratio
Convenience
- Alluzience: No preparation required, reducing potential for dosing errors
- Dysport: Requires mixing, allowing customization of dilution
Clinical Performance
- Onset of action: Both products typically show results within 2-3 days
- Duration: Both last approximately 3-4 months
- Diffusion: Alluzience may have slightly different diffusion characteristics due to its liquid formulation
Indications
- Alluzience: Currently approved only for glabellar lines in Europe
- Dysport: Approved for both cosmetic and therapeutic uses in many countries worldwide
Practitioners who are familiar with Dysport dosing can generally transition to Alluzience using similar dosage patterns, as both use the same unit system. However, they should be aware of the different presentation and potential differences in handling.
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